Co-Scientist

This post details the application of Co-Scientist, a Gemini-powered AI agent, to assist researchers at Calico Life Sciences in the biology of aging. Co-Scientist was used to generate a novel hypothesis about the regulation of the integrated stress response (ISR) by metabolism, which is relevant to aging and disease. The agent also assisted in refining experimental designs to test this hypothesis and incorporate emerging results. The experiments yielded new findings with implications for ISR in health and disease.