Run Key Genomics and Protein Folding Workloads Faster with NVIDIA RTX PRO 4500 Blackwell | NVIDIA Technical Blog
May 26, 2026

Summary
This post introduces the NVIDIA RTX PRO 4500 Blackwell Server Edition GPU and its impact on accelerating key genomics and protein folding workloads. It details performance improvements for NVIDIA Parabricks tools (Minimap2, fq2bam, DeepVariant) showing up to 2.4x speedups compared to the L4 GPU. It also highlights up to 2.3x speedups for protein structure prediction with Openfold3 and cuEquivariance, and up to 9.6x speedups for Smith-Waterman alignment due to new DPX instructions on Blackwell architecture.